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Q: How to find the right settings for all those parameters?
A: It’s easy: concentrate
on the key parameters: force, gap (adjusted by the auger speed) and roll
speed. Start the process in manual mode and switch to automatic mode if
steady state conditions are reached and/or you are familiar with the machine.
Q: What about validation of a movable gap system when auger speed
changes all the time?
A: Validation means to guarantee that always product of the same quality
(here especially porosity) is produced. It doesn’t mean to guarantee that
the process is driven by constant process settings while nobody cares for
the resulting product’s quality.
The first (constant product quality) can easily be achieved by
using the gap control algorithm. If it is necessary to change auger speed
setting to compensate for inhomogeneous powder density, this must not only
be permitted, it even should be claimed in order to obtain a constant porosity.
Because: How can you guarantee constant product quality without doing so?
Q: What about roll adhesion?
A: On the one side, roll adhesion means that adhering powder is compacted
many times (while the actual number of recompression cycles is irreproducible.
Thus you end up with a non validable process), which is unfavourable because
of poor recompactibility. On the other hand, adhering plaques disturb gap
control algorithm, which shoule be avoided. The solution is to use a little
bit (less than used for tabletting) of lubrication agent (Magnesiumstearate
or equivalent).
Q: What happens to powder when it is compacted for a second or third
time in the compactor?
A: While the amount of fines slightly decreases, the compressability
(needed for subsequent tabletting) suffers a lot. If possible, any recompaction
step should be avoided. Moreover two instead of one compaction cycle decreases
the process efficiency by about 50%!
Q: What about thermal considerations?
A1: When rolls of 2.5cm width are used, a temperature increase even
at high pressure is hardly found. This is because a) the surface of those
flat rolls is quite large, which leads to a quick heat exchange with the
suroundings and b) a lot of “cold” powder is brought to the compaction
area and can take a lot of heat without considerable temperature rise.
A2: When wider rolls are used, heat exchange with the surroundings
can not easily be accomplished by the roll surface anymore. Therefore rolls
can be equipped with an active cooling system.
A lot of questions regarding (supposed) hardware malfunctions are answered
by the MAX Expert System, which is available (only for Gerteis machines).